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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKLN1
All Species:
27.88
Human Site:
S418
Identified Species:
51.11
UniProt:
Q9UL63
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UL63
NP_001138826.1
735
84768
S418
C
N
G
S
V
D
D
S
R
A
S
E
P
Q
F
Chimpanzee
Pan troglodytes
XP_001135240
643
74481
E330
V
D
D
S
R
A
S
E
P
Q
F
S
G
L
F
Rhesus Macaque
Macaca mulatta
XP_001098817
735
84767
S418
C
N
G
S
V
D
D
S
R
A
S
E
P
Q
F
Dog
Lupus familis
XP_850354
251
28798
Cat
Felis silvestris
Mouse
Mus musculus
O89050
735
84859
S418
C
N
G
S
V
D
D
S
R
A
S
E
P
Q
F
Rat
Rattus norvegicus
Q99PV3
735
84815
S418
C
N
G
S
V
D
D
S
R
A
S
E
P
Q
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511026
709
82133
S392
C
N
G
S
V
D
D
S
R
A
S
E
P
Q
F
Chicken
Gallus gallus
NP_001025944
733
84525
S416
C
N
G
S
V
D
D
S
R
A
S
E
P
Q
F
Frog
Xenopus laevis
NP_001087072
727
84623
S410
C
N
G
T
V
D
D
S
R
T
N
E
P
Q
F
Zebra Danio
Brachydanio rerio
NP_997859
729
84358
G412
C
N
G
S
V
D
D
G
R
T
S
E
P
Q
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610801
853
97490
P450
N
A
T
G
A
I
E
P
E
Y
S
G
L
F
S
Honey Bee
Apis mellifera
XP_624921
760
87304
E424
V
S
P
T
N
S
T
E
P
I
F
S
G
L
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793226
1390
161226
T436
L
Y
L
Y
H
I
P
T
N
T
W
Q
L
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
99.7
33.8
N.A.
99.1
99.3
N.A.
94.1
96.1
89.9
89.1
N.A.
42.3
54
N.A.
32.6
Protein Similarity:
100
87.4
100
34.1
N.A.
99.5
99.8
N.A.
95.7
98.3
95
95.2
N.A.
61.3
70.9
N.A.
41.9
P-Site Identity:
100
13.3
100
0
N.A.
100
100
N.A.
100
100
80
86.6
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
20
100
0
N.A.
100
100
N.A.
100
100
93.3
86.6
N.A.
13.3
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
0
0
0
47
0
0
0
0
0
% A
% Cys:
62
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
62
62
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
16
8
0
0
62
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
16
0
0
8
70
% F
% Gly:
0
0
62
8
0
0
0
8
0
0
0
8
16
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
16
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
8
0
8
0
0
0
0
0
0
0
0
0
16
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
62
0
0
8
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
8
8
16
0
0
0
62
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
8
0
62
0
% Q
% Arg:
0
0
0
0
8
0
0
0
62
0
0
0
0
0
8
% R
% Ser:
0
8
0
62
0
8
8
54
0
0
62
16
0
0
8
% S
% Thr:
0
0
8
16
0
0
8
8
0
24
0
0
0
0
0
% T
% Val:
16
0
0
0
62
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
8
0
8
0
0
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _